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Adverse effects of 2,4-D dimethylammonium based-herbicide on Acetylcholinesterase expression in Nile tilapia

Chutima Thanomsit1, Prang Khanchanasal2, Witchuda Prasatkaew3

  • 1Department of Fisheries, Faculty of Agriculture and Technology, Rajamangala University of Technology Isan Surin Campus, Surin 32000, Thailand.

Environmental Toxicology and Pharmacology
|February 6, 2024
PubMed

Keywords:
Acetylcholinesterase HerbicideHistologyOptical Coherence Tomography

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Indirect-acting cholinergic agonists are agents that interact with the acetylcholinesterase enzyme in the synaptic cleft, preventing the breakdown of acetylcholine into choline and acetate. Consequently, the concentration of acetylcholine in the synaptic cleft increases. These agonists can be classified into reversible and irreversible inhibitors based on their duration of action.
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