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Racial and ethnic disparities in genomic testing among lung cancer patients: a systematic review

Racial and ethnic disparities in genomic testing among lung cancer patients: a systematic review

Clare Meernik ¹, Yadurshini Raveendran ², Michaela Kolarova ¹, Fariha Rahman ¹, Ebunoluwa Olunuga ³, Emmery Hammond ¹, Akhilesh Shivaramakrishnan ¹, Steph Hendren ⁴, Hayden B Bosworth ^1,5,6,7,8, Devon K Check ¹, Michelle Green ⁹, John H Strickler ², Tomi Akinyemiju ^1,2

Clare Meernik ¹, Yadurshini Raveendran ², Michaela Kolarova ¹

¹Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.
²Duke Cancer Institute, Duke University School of Medicine, Durham, NC, USA.
³Duke University School of Medicine, Durham, NC, USA.
⁴Medical Center Library and Archives, Duke University School of Medicine, Durham, NC, USA.
⁵Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Medical Center, Durham, NC, USA.
⁶Department of Medicine, Division of General Internal Medicine, Duke University Medical Center, Durham, NC, USA.
⁷Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA.
⁸Duke University School of Nursing, Duke University School of Medicine, Durham, NC, USA.
⁹Duke Pathology, Duke University School of Medicine, Durham, NC, USA.

⁰Department of Population Health Sciences, Duke University School of Medicine, Durham, NC, USA.

Journal of the National Cancer Institute +

|

February 6, 2024

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View abstract on PubMed

Summary

This summary is machine-generated.

Racial and ethnic disparities exist in lung cancer genomic testing, with Black patients often receiving it less frequently. These disparities may limit access to precision cancer therapies and impact survival outcomes.

Area Of Science

Oncology
Genomics
Health Disparities

Background

Genomic testing is crucial for precision cancer therapies in lung cancer.
Existing research on racial and ethnic disparities in genomic testing shows mixed results.
Disparities in testing could worsen inequities in cancer treatment and survival.

Conclusions

A majority of studies indicate racial and ethnic disparities in lung cancer genomic testing.
Black patients, in particular, may face barriers to genomic testing, contributing to health inequities.
Despite changing guidelines, disparities persist, highlighting the need for further investigation and intervention.

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