Topic identification, selection, and prioritization for health technology assessment in selected countries: a mixed...

Area of Science:

• Health Policy and Systems Research
• Health Technology Assessment
• Evidence-Informed Policy Making

Background:

• Limited guidance exists for nascent health technology assessment (HTA) systems regarding topic identification, selection, and prioritization (TISP).
• Understanding current TISP processes is crucial for countries developing their HTA frameworks.
• This study addresses the gap in evidence-informed TISP guidance for emerging HTA systems.

Purpose of the Study:

• To explore the range of TISP processes and practices in countries with recently formalized HTA systems.
• To identify aspects of TISP relevant for countries establishing new HTA programs.
• To provide insights for optimizing TISP in emerging HTA contexts.

Main Methods:

• A mixed-methods approach combining systematic literature review, electronic surveys, and individual interviews.
• Systematic literature review to identify countries with recently formalized HTA systems.
• Thematic analysis of documents, survey responses, and interview transcripts to identify TISP lessons.

Main Results:

• Significant variation in TISP approaches, particularly between pharmaceutical and non-pharmaceutical interventions.
• TISP is primarily driven by policymakers and experts, with less stakeholder involvement; horizon scanning is uncommon.
• Political awareness, institutional frameworks, national regulations, and technical capacity influence TISP effectiveness, with collaboration and capacity building identified as future needs.

Conclusions:

• TISP is a critical initial step in HTA, requiring prioritization based on local needs and relevance.
• Limited TISP capacity in emerging HTA settings can be enhanced through local and international collaboration.
• Successful TISP and HTA require integration into national healthcare priority setting and decision-making processes.