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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea

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Association Between Sleep Apnea and Tinnitus: A Meta-Analysis.

Jing Gao¹, Ping Tan¹, Yunliang Liu²

¹Health Medicine Department, The 900th Hospital of the Chinese PLA Joint Logistics Support Force, Fuzhou, Fujian Province, P.R. China.

Ear, Nose, & Throat Journal

|February 7, 2024

Summary

This summary is machine-generated.

Sleep apnea (SA) is linked to a higher prevalence of tinnitus in adults. This association is particularly strong with severe sleep apnea, suggesting a potential connection that warrants further investigation.

Keywords:

meta-analysis observational studies risk factor sleep apnea tinnitus

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Area of Science:

Sleep Medicine
Otolaryngology
Epidemiology

Background:

The relationship between sleep apnea (SA) and tinnitus in adults is not well-established.
Observational studies provide preliminary evidence, necessitating a comprehensive synthesis.

Purpose of the Study:

To systematically review and meta-analyze observational studies investigating the association between sleep apnea and tinnitus in adults.
To quantify the prevalence of tinnitus in adults with sleep apnea.

Main Methods:

A systematic search of major scientific databases (PubMed, Embase, Web of Science, etc.) was conducted.
Eight observational studies (case-control or cross-sectional) involving 132,292 adults were included.
Random-effects or fixed-effects models were employed for meta-analysis based on heterogeneity.

Main Results:

Sleep apnea was associated with a significantly higher prevalence of tinnitus (OR: 1.65).
The association was significant for severe sleep apnea (OR: 2.25) but not for mild or moderate SA.
Geographical differences were observed, with a stronger association in studies from Italy/US compared to China.

Conclusions:

Severe sleep apnea may be a significant risk factor for tinnitus in the adult population.
Further research into the mechanisms linking severe SA and tinnitus is warranted.