Behavioral Assessment of Central Auditory Processing in Turner Syndrome
Adriana Fernandes Duarte Dos Santos1, Martha Marcela Matos Bazilio2, Silvana Frota2
1Programa de Pós-Graduação em Clínica Médica, Faculdade de Medicina UFRJ, Rio de Janeiro, RJ, Brazil.
International Archives of Otorhinolaryngology
|February 7, 2024
Summary
Central auditory processing (CAP) abilities are impaired in Turner syndrome (TS). This study found hearing alterations in TS patients across different age groups and cytogenetic patterns, highlighting the need for audiological monitoring.
Area of Science:
- Neuroscience
- Genetics
- Audiology
Background:
- Turner syndrome (TS) affects approximately 1 in 2,500 live births.
- Hearing alterations are a known comorbidity in individuals with TS.
Purpose of the Study:
- To evaluate central auditory processing (CAP) abilities in individuals with TS.
- To investigate the association between CAP alterations and the cytogenetic patterns in TS.
Main Methods:
- A cohort of 9- to 39-year-old individuals diagnosed with TS underwent a battery of CAP behavioral tests.
- Tests assessed monoaural low-redundancy, dichotic listening, binaural interaction, and temporal processing.
- Data were stratified by age groups and cytogenetic patterns (monosomy X vs. other).
Main Results:
- Alterations in four CAP skills were identified across all age groups.
- A statistically significant difference was observed in the Gaps in Noise Test (GIN) across age groups (p=0.009).
- Individuals with chromosome monosomy X showed more CAP alterations, though not statistically significant.
Conclusions:
- The findings indicate a general impairment in central auditory processing in Turner syndrome.
- These results underscore the importance of audiological assessment and monitoring in individuals with TS.
