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Updated: Jul 4, 2025
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
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Early antiplatelet therapy used for acute ischemic stroke and intracranial hemorrhage
Venkata Buddhavarapu1, Rahul Kashyap2, Salim Surani3
1Department of Medicine, Banner Baywood Medical Center, Mesa, AZ 85206, United States.
World Journal of Clinical Cases
|February 7, 2024
Summary
Aspirin use in acute ischemic stroke is beneficial and recommended. New research suggests potential benefits of early Aspirin administration for small intracranial hemorrhages, though further studies are needed.
Area of Science:
- Neurology
- Clinical Medicine
- Pharmacology
Background:
- The established benefit of Aspirin in acute ischemic stroke management is supported by large trials and clinical guidelines.
- Traditional practice for intracranial hemorrhage (ICH) involves avoiding antiplatelet therapy due to bleeding concerns.
Discussion:
- This editorial comments on research evaluating Aspirin's role in both ischemic stroke and ICH.
- The study by Zhang et al. corroborates Aspirin's efficacy in ischemic stroke and explores its use in low-volume ICH.
Key Insights:
- Aspirin administration within 48 hours of acute ischemic stroke improves functional outcomes.
- Early Aspirin in low-volume ICH (<30 mL) showed no increase in mortality in a small study, warranting further investigation.
Outlook:
- Further large-scale studies are necessary to confirm Aspirin's safety and efficacy in acute ICH.
- The findings may challenge traditional management paradigms for specific ICH patient subgroups.
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