Related Experiment Video
Updated: May 11, 2026

Electrolytic Inferior Vena Cava Model EIM of Venous Thrombosis
Published on: July 12, 2011
Multiple paradoxical embolisms caused by central venous catheter thrombus passing through a patent foramen ovale: A
Jian-Duan Li1, Nian Xu1, Qiang Zhao1
1Department of Cardiology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou 510235, Guangdong Province, China.
Central venous catheter (CVC) thrombus can cause paradoxical embolism (PDE) in both coronary and lower limb arteries in patients with a patent foramen ovale (PFO). This case highlights the importance of considering CVCs as a source of multiple emboli.
Area of Science:
- Cardiology
- Vascular Surgery
- Interventional Cardiology
Background:
- Paradoxical embolism (PDE) is a rare event where a venous thrombus travels to the arterial circulation, typically through a right-to-left shunt.
- Central venous catheters (CVCs) are associated with an increased risk of venous thrombosis.
- Patent foramen ovale (PFO) is a common cardiac anomaly that can facilitate PDE.
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