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Cannabidiol for Postoperative Pain Control After Arthroscopic Rotator Cuff Repair Demonstrates No Deficits in
Michael J Alaia1, Zachary I Li1, Isabel Chalem1
1Department of Orthopedic Surgery, New York University Langone Health, New York, New York, USA.
Orthopaedic Journal of Sports Medicine
|February 7, 2024
Summary
Cannabidiol (CBD) use after rotator cuff repair did not significantly impact long-term pain or patient satisfaction. This study found CBD can be safely included in postoperative pain management without negative effects.
Area of Science:
- Orthopedic surgery
- Pain management
- Pharmacology
Background:
- Cannabidiol (CBD) shows promise for immediate pain relief post-arthroscopic rotator cuff repair (ARCR).
- Long-term effects of perioperative CBD on ARCR outcomes remain unclear.
Purpose of the Study:
- To assess 1-year patient-reported outcomes after ARCR with perioperative CBD versus placebo.
- Evaluate pain, function, and satisfaction in ARCR patients using CBD.
Main Methods:
- A randomized controlled trial (RCT) with 1-year follow-up.
- Patients received either CBD (25-50mg TID) or placebo for 14 days post-ARCR.
- Outcomes included VAS pain, ASES, SANE scores, and patient satisfaction.
Main Results:
- No significant differences in VAS pain, ASES, SANE, or satisfaction at 1-year between CBD and placebo groups.
- High rates of Patient Acceptable Symptom State (PASS) achieved in both groups (81% CBD vs. 77.5% placebo).
Conclusions:
- Perioperative CBD for ARCR did not negatively affect 1-year pain, satisfaction, or functional outcomes.
- CBD can be considered for multimodal pain management post-ARCR without adverse effects.
