Related Experiment Video
Updated: Jul 4, 2025
03:47
A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
Published on: October 25, 2024
224
Tuberculous pleuritis: clinical presentations and diagnostic challenges.
Ken Ka Pang Chan1, Yun Chor Gary Lee2,3
1Department of Medicine & Therapeutics, Chinese University of Hong Kong, Sha Tin, Hong Kong.
Current Opinion in Pulmonary Medicine
|February 7, 2024
Summary
Tuberculous pleuritis (TBP) diagnosis is challenging due to varied presentations and suboptimal tests. New diagnostic tools, including nucleic acid amplification tests (NAAT) and biomarkers, require further validation for clinical use.
Area of Science:
- Pulmonology
- Infectious Diseases
- Microbiology
Background:
- Tuberculous pleuritis (TBP) is a common extrapulmonary tuberculosis form.
- Epidemiological trends vary globally, with increasing incidence in China and decreasing rates in the US.
- TBP presents heterogeneously in clinical symptoms, imaging, and pleural fluid characteristics.
Approach:
- This review highlights current TBP epidemiology.
- It examines the performance of diverse diagnostic strategies.
- Focus is placed on recent advancements in diagnostic tools.
Key Points:
- Conventional microbiological tests for TBP exhibit low sensitivity.
- Nucleic acid amplification tests (NAAT) for pleural fluid show suboptimal sensitivity.
- Pleural fluid biomarkers are under investigation, but consensus on utility and cutoffs is lacking.
Conclusions:
- Heterogeneous clinical presentations complicate TBP diagnosis.
- Enhanced diagnostic tools, including improved NAAT and validated biomarkers, are essential.
- Further research and validation are needed before routine clinical implementation.
Related Concept Videos
01:26Pulmonary Tuberculosis IV
143
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
143
01:28Pleural Effusion II: Symptoms and Management
176
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
176
01:31Pulmonary Tuberculosis III
332
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
332
01:30Pleural Disorders: Types and Brief Description
208
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
208
01:27Pneumothorax-II
150
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
150
01:28Pulmonary Tuberculosis II
239
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
239