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Updated: Jul 4, 2025

A Model of Experimental Steatosis In Vitro: Hepatocyte Cell Culture in Lipid Overload-Conditioned Medium
Published on: May 18, 2021
[Metabolic steatotic liver disease: the move towards an inclusive definition]
Lucia Zampaglione1, Noémie Marello1, Pierre-Auguste Petignat1
1Service de médecine interne générale, Centre hospitalier du Valais romand, Hôpital de Sion, 1951 Sion.
Abstract:
Steatotic liver disease is the most common liver pathology worldwide, comprises a wide range of liver diseases linked to metabolic dysfunction, excessive alcohol consumption, drug reactions and infectious and genetic origins. Following several years of deliberation, the major liver disease societies have recently adopted a new nomenclature and updated diagnostic criteria for steatotic liver diseases, aimed at better reflecting our evolving understanding of their pathophysiology. This article summarizes these newly adopted designations, explores the basis for these nomenclatures, presents recent epidemiological data and discusses new diagnostic criteria and recent advances in therapeutic approaches for steatotic liver disease.
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