Related Experiment Video
Updated: Jul 4, 2025

Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
Home Insulin Pump Use in Hospitalized Children With Type 1 Diabetes
Jodi Owens1, Joshua Courter2, Christine L Schuler3,4
1Division of Endocrinology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Insights
Home insulin pumps are safe for hospitalized children with diabetes, showing lower hyperglycemia rates and no diabetic ketoacidosis (DKA) cases. This supports their use in pediatric hospital settings for eligible patients.
Area of Science:
- Pediatric Endocrinology
- Diabetes Technology
- Inpatient Care
Background:
- Limited pediatric data exists on home insulin pump safety during inpatient stays.
- Understanding safety is crucial for integrating diabetes technology into pediatric hospitals.
Purpose of the Study:
- To evaluate the safety and accuracy of home insulin pump delivery in hospitalized children managed by patients or caregivers.
Main Methods:
- Retrospective, observational cohort study of children with insulin-dependent diabetes admitted between 2016-2021.
- Compared outcomes (hyperglycemia, hypoglycemia, DKA) across home insulin pumps, hospital insulin pumps, and subcutaneous injections.
Main Results:
- Home insulin pumps showed lower hyperglycemia rates (27.0%) compared to injections (45.2%).
- Hypoglycemia rates were comparable across all insulin delivery methods.
- No cases of diabetic ketoacidosis (DKA) occurred in patients using home or hospital insulin pumps.
Conclusions:
- Home insulin pump use is safe for hospitalized pediatric patients regarding hyperglycemia and hypoglycemia.
- Data supports the use of home insulin pumps for non-critically ill pediatric patients without active DKA.
Importance:
Pediatric data on inpatient home insulin pumps are absent in the literature. Understanding safety of home insulin pumps, managed by patients or caregivers, during times of illness will help diabetes technology securely move into pediatric hospitals.
Objective:
To examine whether insulin can be safely and accurately delivered to hospitalized children through home insulin pumps when managed by patients or caregivers.
Design, Setting, And Participants:
This single-center, retrospective, observational cohort study included children with insulin-dependent diabetes admitted to a tertiary children's hospital from January 1, 2016, to December 31, 2021. In all these patients, diabetes was the primary or secondary diagnosis on admission.
Exposure:
Insulin delivery via home insulin pump, hospital insulin pump, or subcutaneous injection.
Main Outcomes And Measures:
Hyperglycemia (glucose, >250 mg/dL) and hypoglycemia (glucose, <45 mg/dL) rates (quantified as the proportion of total insulin-days), glucose variability, and diabetic ketoacidosis (DKA) recurrences were compared for hospital pumps (manual mode), home pumps (manual mode), and subcutaneous injections using bivariate tests.
Results:
There were 18 096 insulin-days among 2738 patients aged 0.5 to 25 years (median age, 15.8 years [IQR, 12.3-18.3 years]). Overall, 990 (5.5%) of insulin-days involved hospital insulin pumps, and 775 (4.3%) involved home pumps. A total of 155 insulin-days (15.7%) involving hospital pumps were hyperglycemic, compared with 209 (27.0%) involving home pumps and 7374 (45.2%) involving injections (P < .001). Moderate hypoglycemia days comprised 31 insulin-days (3.1%) involving hospital pumps compared with 35 (4.5%) involving home pumps and 830 (5.1%) involving injections (P = .02). Severe hypoglycemia did not differ significantly according to insulin delivery method. Two patients using injections (0.01%) developed DKA; no patients using hospital or home pumps developed DKA.
Conclusions And Relevance:
In this cohort study, home insulin pump use was found to be safe in a children's hospital regarding hyperglycemia and hypoglycemia. These data support use of home insulin pumps during pediatric admissions in patients who do not require intensive care and without active DKA.
Related Concept Videos
Insulin: Dosing Regimen and Adverse Effects
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Insulin Formulations: Types and Delivery
Short-acting insulins are divided into...
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Glucose Homeostasis: Pancreatic Islets and Insulin Secretion
Insulin and C-peptide are...
Hypoglycemia and Glucagon
Insulin: Biosynthesis, Chemistry, and Preparation
Damage or functional impairment of β-cells inhibits insulin production, leading to diabetes. Diabetes treatment...

