Myocardial Injury Progression after Radiofrequency Ablation in School-Age Children
Sissy Lara de Melo1, Alberto Pereira Ferraz1, Stephanie Ondracek Lemouche1
1Instituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo , São Paulo , SP - Brasil.
Radiofrequency catheter ablation for pediatric arrhythmias showed no increased risk of myocardial injury progression or coronary artery lesions. This study provides crucial safety data for this important pediatric intervention.
Area of Science:
- Cardiology
- Pediatric Electrophysiology
- Medical Imaging
Background:
- Catheter ablation is a common treatment for arrhythmias.
- While safe in adults, data on pediatric patients is limited.
- Concerns exist regarding scar expansion and long-term effects in children.
Purpose of the Study:
- To assess the risk of myocardial injury progression after radiofrequency catheter ablation in pediatric patients.
- To evaluate potential coronary artery damage following ablation in this age group.
Main Methods:
- Retrospective study of 20 pediatric patients.
- Cardiac magnetic resonance and coronary angiography were used for follow-up.
- Evaluated myocardial fibrosis and coronary artery integrity.
Main Results:
- Median age at ablation was 15.1 years; follow-up MRI at median 21 years.
- Most common diagnoses: nodal reentry tachycardia and Wolff-Parkinson-White Syndrome.
- Minor ventricular myocardial fibrosis (<0.6 cm³) in 3 patients; no ventricular dysfunction or coronary lesions observed.
Conclusions:
- Radiofrequency catheter ablation in pediatric patients did not lead to increased myocardial injury progression.
- No evidence of coronary artery lesions was found post-ablation.
- The procedure appears safe regarding myocardial and coronary integrity in this population.
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