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CineECG for visualization of changes in ventricular electrical activity during ischemia
I van der Schaaf1, M Kloosterman1, A P M Gorgels2
1Department of Cardiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, the Netherlands.
Journal of Electrocardiology
|February 7, 2024
Summary
CineECG visualizes ventricular electrical activity, detecting immediate changes during induced ischemia. This technology may aid early acute ischemia detection before distinct ECG changes appear.
Area of Science:
- Cardiology
- Medical Imaging
- Electrophysiology
Background:
- CineECG visualizes ventricular electrical activity using 12-lead ECG.
- CineECG has not previously been used to visualize ventricular activation during ischemia.
Purpose of the Study:
- To assess changes in ventricular activity during acute ischemia using CineECG.
- To correlate these changes with standard ECG findings.
Main Methods:
- Analyzed continuous ECGs from the STAFF III database during percutaneous coronary intervention.
- Applied CineECG at baseline and during 150 seconds of balloon inflation.
- Quantified changes in CineECG direction (Δangle) and ST-segment amplitude (rmsA).
Main Results:
- 94 patients were analyzed.
- Significant median Δangle changes observed for initial QRS, terminal QRS, ST-segment, and T-wave within 150 seconds of ischemia.
- Median ST-segment root mean square amplitude (rmsA) increased at the start of inflation.
Conclusions:
- CineECG detected immediate alterations in ventricular electrical activity during induced ischemia.
- These changes were apparent even when ST-segment ECG changes were subtle.
- CineECG shows potential for early acute ischemia detection.
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