Assessing the optimal MRI descriptors to diagnose Ménière's disease and the added value of analysing the vestibular aqueduct
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View abstract on PubMed
Summary
This summary is machine-generated.Delayed MRI with specific descriptors accurately detects Ménière
Area Of Science
- Radiology
- Neurology
- Otolaryngology
Background
- Ménière's disease (MD) diagnosis relies on clinical criteria, with imaging playing a supportive role.
- Delayed post-gadolinium MRI offers potential for objective MD detection.
Purpose Of The Study
- To assess the diagnostic performance of MRI descriptors for Ménière's disease (MD).
- To identify optimal MRI descriptor combinations and the utility of vestibular aqueduct (VA) analysis.
Main Methods
- Retrospective case-control study of 227 patients with Ménièriform symptoms.
- Evaluation of 17 MRI descriptors, including saccular abnormality and perilymphatic enhancement (PLE).
- Logistic regression and ROC analysis to determine optimal descriptor combinations.
Main Results
- Saccular abnormality demonstrated the highest diagnostic odds ratio (DOR).
- Vestibular aqueduct (VA) descriptors showed excellent reliability.
- A combination of saccular abnormality, asymmetric cochlear PLE, and incomplete VA visualization achieved 90.2% correct classification.
Conclusions
- Saccular abnormalities are the strongest individual MRI predictors of MD.
- Incomplete VA visualization adds diagnostic value.
- Optimized MRI protocols can improve MD diagnosis.
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