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The association between common mental disorders and tuberculosis: a case-control study from Guinea-Bissau
Lena Larson1,2, Grethe Lemvik1,2, Frauke Rudolf1,2
1Bandim Health Project, Bissau, Guinea-Bissau.
Acta Neuropsychiatrica
|February 8, 2024
Summary
Tuberculosis patients exhibit higher rates of common mental disorders (CMDs) at diagnosis. However, after completing TB treatment, psychological distress levels return to those of the general population.
Area of Science:
- Global Health
- Infectious Diseases
- Mental Health
Background:
- Tuberculosis (TB) is a significant global health challenge.
- High TB prevalence areas often face co-occurring health issues.
- The relationship between TB and common mental disorders (CMDs) requires further investigation.
Purpose of the Study:
- To investigate the association between tuberculosis (TB) and common mental disorders (CMDs).
- To assess CMD prevalence in a high TB prevalence area.
- To compare CMD rates in TB patients versus the general population.
Main Methods:
- A case-control study was conducted in Guinea-Bissau.
- TB patients and healthy controls were recruited.
- Screening for CMDs utilized the Kessler 10 (K-10) and Hopkins Symptom Checklist 25 (SCL-8d).
Main Results:
- TB patients showed significantly higher CMD prevalence at diagnosis (33.6% SCL-8d, 46.2% K-10) compared to controls (6.8% SCL-8d, 6.7% K-10).
- Adjusted odds ratios for CMDs were 7.18 (SCL-8d) and 14.52 (K-10).
- No significant difference in CMD prevalence was found between TB patients after 6 months of treatment and controls.
Conclusions:
- Psychological distress and CMDs are more common in TB patients at the time of diagnosis.
- Successful TB treatment appears to alleviate psychological distress.
- This highlights the importance of integrated care for TB and mental health.
Keywords:
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