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Results and Follow-Up of a Sequential Q-Switched Laser Therapy for Nevus of Ota in Infants
Han Zheng1, Ai-E Xu1, Gang Qiao1
1Laser Center, Hangzhou Third People's Hospital, Zhejiang, 310009, People's Republic of China.
Insights
Early laser therapy is highly effective and safe for treating nevus of Ota in infants. This treatment offers significant physical and psychological benefits, with high satisfaction rates and minimal adverse effects.
Area of Science:
- Pediatric Dermatology
- Laser Medicine
- Infant Health
Background:
- Limited research exists on laser therapy for infantile nevus of Ota.
- Nevus of Ota can have significant physical and psychological impacts on infants.
Purpose of the Study:
- To evaluate the efficacy and safety of early-stage laser therapy for nevus of Ota in infants.
- To assess treatment outcomes and adverse reactions in infants receiving laser therapy.
Main Methods:
- 102 infants under one year with nevus of Ota received combined 755 nm and 1064 nm Q-switched laser therapy.
- Treatments were spaced six months apart, with photographic documentation and follow-up questionnaires.
- Parental questionnaires assessed general well-being and behavioral symptoms.
Main Results:
- High efficacy observed: 88.7% after 4 sessions, 99.3% after 7 sessions.
- No serious adverse reactions reported besides pain; 29.8% recurrence rate influenced by lesion factors.
- Subsequent treatments effectively managed recurrences; high parental satisfaction and no psychological distress noted.
Conclusions:
- Prompt laser therapy for infantile nevus of Ota is recommended.
- Early intervention improves infant well-being, addressing both physical and psychological concerns.
- Laser therapy demonstrates a favorable safety and efficacy profile for this condition.
Background And Aim:
There is a dearth of scholarly investigation pertaining to the effectiveness and safety of laser therapy for nevus of Ota manifestation in infants. The objective of this study is to examine the efficacy and safety of administering laser therapy at an early stage to treat nevus of Ota in infants.
Methods:
A total of 102 infants below the age of one who had nevus of Ota were treated at the Laser Center at Hangzhou Third People's Hospital. The treatment approach involved a combination of the Q-switched laser (with a wavelength of 755 nm) and the Q-switched laser (with a wavelength of 1064 nm). The treatment sessions were conducted at six-month intervals. Prior to and after each session, photographs and relevant parameters were documented, including any skin reactions. Subsequent follow-up was conducted through phone calls, WeChat, and text messages, and the parents/guardians of the infants completed a general questionnaire as well as Conner's Abbreviated Symptom Questionnaire.
Results:
Laser therapy exhibited significant efficacy in the treatment of nevus of Ota in infants. Success rates reached 88.7% after four sessions and 99.3% after seven sessions. No instances of serious adverse reactions, except for pain, were reported. Among the 47 infants subject to follow-up, 14 experienced a recurrence, resulting in a recurrence rate of 29.8%. Factors contributing to these recurrences included lesion size, subtypes, exposure to the sun, and location. Subsequent laser treatments, typically involving two to three additional sessions, proved effective in mitigating recurrences. Notably, none of the infants exhibited any signs of fear, anxiety, or other psychological abnormalities following laser therapy, and the overall satisfaction rate was markedly high.
Conclusion:
Commencing laser therapy promptly for nevus of Ota in infants is recommended. This early intervention significantly contributes to the overall well-being of infants, addressing both physical and psychological aspects.
