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A Structured Rehabilitation Protocol for Improved Multifunctional Prosthetic Control: A Case Study
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Pain-sensorimotor interactions: New perspectives and a new model.

Greg M Murray1, Barry J Sessle2

  • 1Discipline of Restorative and Reconstructive Dentistry, Sydney School of Dentistry, Faculty of Medicine and Health, The University of Sydney, Darcy Road, Westmead, NSW 2145, Australia.

Neurobiology of Pain (Cambridge, Mass.)
|February 8, 2024
PubMed
Summary
This summary is machine-generated.

Pain and sensorimotor behavior are complexly linked. Recent theories incorporate pain dimensions, but a new Theory of Pain-Sensorimotor Interactions (TOPSMI) offers a comprehensive biopsychosocial framework for customized pain treatments.

Keywords:
AnimalsElectromyographyEpigenomicsGeneticsHumansMotor activityNeuronal plasticityNociceptionPainPsychosocial functioning

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Area of Science:

  • Neuroscience
  • Pain Research
  • Rehabilitation Science

Background:

  • The interaction between pain and sensorimotor behavior is a long-standing research area.
  • Previous theories on pain-sensorimotor interactions have limitations in fully explaining these complex relationships.

Purpose of the Study:

  • To review existing theories on pain-sensorimotor interactions.
  • To identify limitations and propose a more comprehensive framework for understanding these interactions.

Main Methods:

  • Literature review of experimental and clinical studies on pain-sensorimotor interactions.
  • Analysis of strengths and limitations of current and previous theoretical models.
  • Development of a new theoretical concept, the Theory of Pain-Sensorimotor Interactions (TOPSMI).

Main Results:

  • Recent theories have improved by incorporating sensory, affective, and cognitive pain dimensions.
  • Additional factors like biopsychosocial influences (genetics, psychology, social factors) and mechanistic frameworks (nociception, neuroplasticity) are crucial.
  • Existing theories require further refinement to encompass the full complexity of pain-sensorimotor interactions.

Conclusions:

  • The proposed Theory of Pain-Sensorimotor Interactions (TOPSMI) provides a more comprehensive framework.
  • TOPSMI integrates biological, psychological, and social factors for a holistic understanding.
  • This new perspective supports the development of customized pain management strategies aligned with the biopsychosocial model.