Related Experiment Video

Updated: Jul 4, 2025

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
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Published on: January 7, 2019

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Targetable leukemia dependency on noncanonical PI3Kγ signaling.

Qingyu Luo, Evangeline G Raulston, Miguel A Prado

    Biorxiv : the Preprint Server for Biology
    |February 8, 2024
    PubMed
    Summary

    This study identifies a new target, phosphoinositide 3-kinase gamma (PI3Kγ), crucial for high-risk acute leukemias. Inhibiting PI3Kγ with eganelisib shows promise, especially combined with cytarabine, for treating leukemia.

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