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Characterization of Recombination Effects in a Liquid Ionization Chamber Used for the Dosimetry of a Radiosurgical Accelerator

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Validation of complex radiotherapy techniques using polymer gel dosimetry.

Christian P Karger^1,2, Alina Elter^1,2,3, Stefan Dorsch^1,2

¹Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.

Physics in Medicine and Biology

|February 8, 2024

Summary

Polymer gel dosimeters offer 3D dose verification for advanced radiotherapy, validating complex treatments like intensity-modulated radiation therapy and proton beam therapy. These end-to-end tests ensure accurate dose delivery and patient safety in modern radiation oncology.

Keywords:

MR-guided RT adaptive radiotherapy (RT)inter- and intrafractional motion polymer gel dosimetry proton and ion beam RT verification of 3D dose distributions

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Area of Science:

Radiation Oncology
Medical Physics
Dosimetry

Background:

Modern radiotherapy requires precise dose delivery to irregular targets while sparing normal tissues.
Complex radiotherapy techniques necessitate robust end-to-end testing for workflow validation.
Polymer gel dosimeters are crucial for capturing 3D dose distributions in radiotherapy.

Purpose of the Study:

To review the principles, formulation, and evaluation methods of polymer gel dosimetry.
To assess the validation of advanced radiotherapy techniques using polymer gel dosimeters.
To discuss the current status, limitations, and future challenges of gel dosimetry in radiotherapy.

Main Methods:

Review of existing studies on polymer gel dosimetry.
Evaluation of device-specific geometrical parameters and dose delivery.
Analysis of applications in 3D-CRT/IMRT, stereotactic radiosurgery, moving targets, MRI-guided radiotherapy, and particle beam therapy.

Main Results:

Polymer gel dosimetry enables 3D dose verification for various advanced radiotherapy techniques.
Studies validate geometrical accuracy and dose delivery for techniques including IMRT and proton therapy.
Gel dosimetry has been applied to moving targets and online-adaptive radiotherapy.

Conclusions:

Polymer gel dosimetry is a valuable tool for validating complex radiotherapy workflows.
Despite limitations, it plays a vital role in ensuring treatment accuracy and patient safety.
Further research is needed to address challenges and enhance the application of gel dosimetry.