Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

546
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
546
Neural Regulation01:37

Neural Regulation

39.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.4K
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

268
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
268

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Digital profiling of dysarthria in late- and early-onset Parkinson's disease.

Journal of Parkinson's disease·2026
Same author

Multidomain lifestyle intervention for the prevention of cognitive decline in at-risk older adults in Latin America (LatAm-FINGERS): a single-blind, multicentre, randomised controlled trial.

Lancet (London, England)·2026
Same author

The include network: Advancing cross-linguistic equity in brain health research.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Semantic memory navigation in mild cognitive impairment: Automated markers with neural and biofluid correlates.

NeuroImage·2026
Same author

Mind Melodies: An NLP platform to examine music cognition.

Behavior research methods·2026
Same author

Redefining the norms: an interdisciplinary perspective on language testing in multilinguals with acquired and progressive neurogenic disorders.

Alzheimer's & dementia (Amsterdam, Netherlands)·2026

Related Experiment Video

Updated: Jul 4, 2025

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.8K

Electrophysiological alterations during action semantic processing in Parkinson's disease.

Mariano N Díaz Rivera1, Lucía Amoruso2, Yamile Bocanegra3

  • 1Centro de Neurociencias Cognitivas, Universidad de San Andrés (UdeSA), Buenos Aires, Argentina; National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.

Neurobiology of Aging
|February 8, 2024
PubMed
Summary

Parkinson's disease (PD) disrupts neurophysiology during action understanding, even when time isn't critical. This study reveals distinct brain patterns in PD patients compared to healthy individuals, impacting semantic processing.

Keywords:
Action semanticsEvent-related potentialsNeurocognitive markersParkinson’s diseaseTime-frequency modulations

More Related Videos

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder
08:17

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

10.6K
Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

15.7K

Related Experiment Videos

Last Updated: Jul 4, 2025

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

7.8K
A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder
08:17

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

10.6K
Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

15.7K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Neurology

Background:

  • Action semantics assessments show Parkinson's disease (PD) markers.
  • Neurophysiological signatures of action semantics are under-examined in PD, particularly without time constraints.

Purpose of the Study:

  • To investigate event-related potentials and time-frequency modulations in PD patients and healthy individuals (HPs) during a delayed-response semantic judgment task.
  • To identify neurophysiological differences in action-concept processing between HPs and PD patients.

Main Methods:

  • Assessed event-related potentials and time-frequency modulations.
  • Utilized a delayed-response semantic judgment task with related and unrelated action-picture pairs.
  • Compared PD patients and healthy individuals.

Main Results:

  • Both groups responded faster to related than unrelated trials.
  • Healthy individuals showed greater N400 amplitudes and theta enhancement/mu desynchronization for unrelated trials.
  • PD patients lacked typical N400 and theta modulations and showed a contralateralized mu-range cluster.

Conclusions:

  • Parkinson's disease involves multidimensional neurophysiological disruptions in action-concept processing.
  • These disruptions occur even when task demands do not impose strict time constraints.
  • Findings necessitate revisions to translational neurocognitive models of Parkinson's disease.