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SIRT2 regulates apoptosis by inducing mitophagy in sheep cumulus cells

Xiaohuan Fang1, Wei Xia2, Yatian Qi1

  • 1College of Animal Science and Technology, Hebei Agricultural University, Baoding, 071000, PR China.

Theriogenology
|February 8, 2024
PubMed
Summary

Sirtuin 2 (SIRT2) regulates cumulus cell apoptosis by controlling mitophagy. Inhibiting mitophagy prevents apoptosis, and MAPK15 plays a key role in this SIRT2-mediated process.

Keywords:
ApoptosisMitophagySIRT2Sheep cumulus cells

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