Bacterial Cellulose-Based MOF Hybrid as a Sensitive Switch Off-On Luminescent Sensor for the Selective Recognition of...

In this study, a stable and luminescent UiO-66-NH₂ (UN) and its derivative Cu²⁺@UN were prepared and utilized successfully as an Off-On luminescent sensing platform for effective, selective, as well as rapid (5 min) detection of l-Histidine (l-His). The UN reveals efficient quenching in the presence of Cu²⁺ ions through photoinduced electron transition (PET) mechanism as a dynamic quenching process (in the range of 0.01-1 mM) forming Cu²⁺@UN sensing platform. However, due to the remarkable affinity between l-His and Cu²⁺, the luminescence of Cu²⁺@UN is recovered in the presence of l-His indicating Turn-On behavior via a quencher detachment mechanism (QD). A good linear relationship between the l-His concentration and luminescence intensity was observed in the range of 0.01-40 μM (R² = 0.9978) with a detection limit of 7 nM for l-His sensing. The suggested method was successfully utilized for l-His determination in real samples with good recoveries and satisfying consequences. Moreover, the result indicates that only l-His induces a significant luminescence restoration of Cu²⁺@UN and that the signal is significantly greater than that of the other amino acids. Also, the portable test paper based on bacterial cellulose (BC) as the Cu²⁺@UNBC sensing platform was developed to conveniently evaluate the effective detection of l-His.