[Intrasellar syndrome. Analysis of 506 cases of transsphenoidal surgery]

The author has performed 506 transsphenoidal surgeries but has analyzed in this study only 404 cases. There were 396 hypophyseal tumors, 4 intrasellar cysts and 4 empty sellas. Based in the symptoms presented by the patients he describes an "intrasellar syndrome", characterized by headache, visual disorders and hormonal abnormalities. He calls attention for intrasellar tumors with normal sella, as seen by x-ray. The diagnosis of these tumors were made only by endocrinological studies. At last he shows the advantages of transsphenoidal surgery in this pathology and the excellent results obtained. The mortality of his cases was only 0.2%.