Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Covalent Bonding and Lewis Structures02:46

Covalent Bonding and Lewis Structures

49.3K
Compared to ionic bonds, which results from the transfer of electrons between metallic and nonmetallic atoms, covalent bonds result from the mutual attraction of atoms for a “shared” pair of electrons.
49.3K
Hybridization of Atomic Orbitals I03:24

Hybridization of Atomic Orbitals I

47.1K
The mathematical expression known as the wave function, ψ, contains information about each orbital and the wavelike properties of electrons in an isolated atom. When atoms are bound together in a molecule, the wave functions combine to produce new mathematical descriptions that have different shapes. This process of combining the wave functions for atomic orbitals is called hybridization and is mathematically accomplished by the linear combination of atomic orbitals. The new orbitals that...
47.1K
Exceptions to the Octet Rule02:55

Exceptions to the Octet Rule

28.2K
Many covalent molecules have central atoms that do not have eight electrons in their Lewis structures. These molecules fall into three categories:
28.2K
Hydroboration-Oxidation of Alkenes03:08

Hydroboration-Oxidation of Alkenes

8.2K
In addition to the oxymercuration–demercuration method, which converts the alkenes to alcohols with Markovnikov orientation, a complementary hydroboration-oxidation method yields the anti-Markovnikov product. The hydroboration reaction, discovered in 1959 by H.C. Brown, involves the addition of a B–H bond of borane to an alkene giving an organoborane intermediate. The oxidation of this intermediate with basic hydrogen peroxide forms an alcohol.
8.2K
Covalent Bonds01:08

Covalent Bonds

7.4K
Overview
When two atoms share electrons to complete their valence shells, they create a covalent bond. An atom's electronegativity—the force with which shared electrons are pulled towards an atom—determines how the electrons are shared. Molecules formed with covalent bonds can be either polar or nonpolar. Atoms with similar electronegativities form nonpolar covalent bonds; the electrons are shared equally. Atoms with different electronegativities share electrons unequally,...
7.4K
Lewis Structures of Molecular Compounds and Polyatomic Ions02:54

Lewis Structures of Molecular Compounds and Polyatomic Ions

34.8K
To draw Lewis structures for complicated molecules and molecular ions, it is helpful to follow a step-by-step procedure as outlined:
34.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A universal deep learning framework for empowering nanopore identification by reinforcing temporal signals.

Nature communications·2026
Same author

Screening of aggregation properties of cyclic peptides by protein nanopores.

Analytical methods : advancing methods and applications·2026
Same author

Architecting bioinspired nanocrystalline domains for ultimate robust and transparent cellulose photonic hydrogels.

Science advances·2026
Same author

Precise discrimination of G-quadruplex conformation by chiral nanoassembly with photo-reversibility.

Nature communications·2026
Same author

Single-Feature Identification of α2-8 Linked Sialoglycans Using Engineered Aerolysin Nanopores: A Paradigm for Glycan Linkage Analysis.

Journal of the American Chemical Society·2026
Same author

Nanopore Fingerprinting of Structurally Diverse Amino Acid-Conjugated Bile Acids.

Nano letters·2025

Related Experiment Video

Updated: Jul 4, 2025

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

69.1K

Water-stable boroxine structure with dynamic covalent bonds.

Xiaopei Li1,2, Yongjie Zhang2, Zhenqiang Shi1

  • 1CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, P. R. China.

Nature Communications
|February 8, 2024
PubMed
Summary

A novel water-stable boroxine structure was discovered from 2-hydroxyphenylboronic acid. This breakthrough enables new applications for boroxines in aqueous environments, including fluoride ion detection and hydrogel development.

More Related Videos

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis
13:09

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis

Published on: January 6, 2016

14.8K
Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants
08:56

Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants

Published on: March 25, 2017

7.6K

Related Experiment Videos

Last Updated: Jul 4, 2025

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

69.1K
Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis
13:09

Assessment of Boron Doped Diamond Electrode Quality and Application to In Situ Modification of Local pH by Water Electrolysis

Published on: January 6, 2016

14.8K
Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants
08:56

Synthesis of 1,2-Azaborines and the Preparation of Their Protein Complexes with T4 Lysozyme Mutants

Published on: March 25, 2017

7.6K

Area of Science:

  • Materials Science
  • Supramolecular Chemistry
  • Organic Chemistry

Background:

  • Boroxines are crucial in developing advanced materials like covalent organic frameworks and self-healing substances.
  • The application of boroxines in aqueous media has been severely limited by their inherent hydrolytic instability.
  • Existing boroxine structures degrade rapidly in water, hindering their use in biological and environmental applications.

Purpose of the Study:

  • To report the discovery and characterization of a novel, water-stable boroxine structure.
  • To investigate the transformation mechanism of 2-hydroxyphenylboronic acid into a stable boroxine in aqueous conditions.
  • To explore the potential applications of this water-stable boroxine in fluoride ion sensing and hydrogel formation.

Main Methods:

  • Spontaneous dehydration of 2-hydroxyphenylboronic acid under ambient conditions to form a dimer.
  • Exposure of the dimer to water to induce transformation into a boroxine structure.
  • Characterization of the boroxine's stability, dynamic covalent bonds, and aggregation-induced emission (AIE) properties.
  • Testing the boroxine's binding capacity for fluoride ions in aqueous solutions.
  • Development and evaluation of a boroxine-based hydrogel for reversible gel-sol transitions.

Main Results:

  • 2-hydroxyphenylboronic acid spontaneously dehydrates to form a dimer with dynamic covalent bonds and aggregation-induced enhanced emission.
  • The dimer rapidly transforms into a highly pH-stable, water-compatible boroxine structure upon contact with water.
  • The water-stable boroxine exhibits strong binding affinity for fluoride ions in aqueous media.
  • A novel boroxine-based hydrogel was successfully developed, demonstrating high acid-base stability and reversible gel-sol transitions.

Conclusions:

  • A water-stable boroxine has been successfully synthesized from 2-hydroxyphenylboronic acid, overcoming previous limitations.
  • This discovery enables the use of boroxines in aqueous environments, expanding their application scope.
  • The developed boroxine-based materials show promise for fluoride sensing and advanced hydrogel applications, heralding a new era in boroxine chemistry.