Related Experiment Video
Updated: Jul 4, 2025
10:14
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
3.1K
Linear streaks associated with retinitis pigmentosa
Maurizio Battaglia Parodi1, Alessandro Arrigo1, Emanuela Aragona1
1Department of Ophthalmology, IRCCS San Raffaele Scientific Institute, via Olgettina, 60, 20132, Milan, Italy.
European Journal of Ophthalmology
|February 9, 2024
Summary
Peripheral linear streaks are an infrequent finding in retinitis pigmentosa (RP). This rare phenotypical manifestation may suggest inflammation
Area of Science:
- Ophthalmology
- Genetics
- Retinal Diseases
Background:
- Retinitis pigmentosa (RP) is a group of inherited retinal diseases.
- RP causes progressive vision loss.
- Phenotypical variations in RP are common.
Purpose of the Study:
- To describe a specific phenotypical manifestation of RP.
- Identify peripheral linear streaks in patients with RP.
Main Methods:
- Prospective observational case series.
- Ophthalmological examination of consecutive RP patients.
- Diagnosis based on identifying peripheral retinal atrophic streaks.
Main Results:
- Peripheral linear streaks were found in 6 of 140 (4.2%) RP patients.
- One patient had posterior pole lesions and developed macular neovascularization.
- This patient was treated with ranibizumab injections.
Conclusions:
- Peripheral linear streaks are an infrequent RP phenotype.
- This finding may support the role of inflammation in RP pathogenesis.
Related Concept Videos
01:22Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K
01:20Anatomy of the Eyeball
7.1K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.1K