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Pulmonary interstitial glycogenosis in two neonates: Early recognition and use of corticosteroids
Eric Hamberger1, Yolanda Yu1, Hyo-Jung Choi2
1Department of Pediatrics, Division of Pediatric Pulmonology and Sleep Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Abstract:
Pulmonary interstitial glycogenosis (PIG) is known to be associated with a wide variety of congenital conditions, though the extent to which PIG contributes to clinical presentation and outcomes in infants remains controversial. We describe two cases of infants with congenital anomalies and respiratory distress at birth who were diagnosed with PIG with differing clinical courses and response to methylprednisolone therapy. These cases highlight the importance of improved recognition of PIG and uncertainties about which patients may benefit from treatment.
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