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Related Concept Videos

Brain Imaging01:14

Brain Imaging

229
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
229

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Related Experiment Video

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Bilateral Assessment of the Corticospinal Pathways of the Ankle Muscles Using Navigated Transcranial Magnetic Stimulation
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Recent developments and future avenues for human corticospinal neuroimaging.

Merve Kaptan1, Dario Pfyffer1, Christiane G Konstantopoulos1

  • 1Division of Pain Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Palo Alto, CA, United States.

Frontiers in Human Neuroscience
|February 9, 2024
PubMed
Summary

Corticospinal imaging advances our understanding of brain-spinal cord communication for sensorimotor functions. This technique offers new insights into neurological disorders and potential biomarkers.

Keywords:
combined brain and spinal cord fMRIcorticospinal fMRIcorticospinal imagingfMRI data analysismotor taskspain processingresting-state fMRI

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Area of Science:

  • Neuroimaging
  • Central Nervous System (CNS) research
  • Spinal cord imaging

Background:

  • Non-invasive neuroimaging primarily focuses on the brain, neglecting the spinal cord's role in CNS functions.
  • Understanding sensorimotor processing and neurological conditions requires simultaneous brain and spinal cord examination.
  • Spinal cord imaging, though challenging, is crucial for studying brain-peripheral communication.

Purpose of the Study:

  • To review literature on advanced corticospinal imaging techniques.
  • To explore the flow of sensorimotor information between the brain and spinal cord.
  • To discuss functional magnetic resonance imaging (fMRI) advancements and future perspectives in CNS research.

Main Methods:

  • Review of studies utilizing specialized corticospinal imaging protocols.
  • Assessment of sensorimotor, autonomic, and interneuronal signaling via imaging.
  • Analysis of interactions between spinal cord activity and cortical processes.

Main Results:

  • Corticospinal imaging successfully assesses spinal cord functions and their brain interactions.
  • Studies reveal insights into sensorimotor signaling pathways.
  • Emerging techniques enable simultaneous brain and spinal cord activity monitoring.

Conclusions:

  • Combined corticospinal fMRI is vital for understanding CNS sensorimotor processing.
  • Advancements in imaging techniques promise improved diagnostics for neurological disorders.
  • Refined methodologies can lead to clinically relevant biomarkers for CNS conditions.