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Updated: Jul 4, 2025

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo

Multi-Scale Modification of Metallic Implants With Pore Gradients, Polyelectrolytes and Their Indirect Monitoring In vivo

Published on: July 1, 2013

Silicone Migration from Intact Saline Breast Implants.

Siham Azahaf¹, Karlinde A Spit¹, Christel J M de Blok¹

¹From Section General Internal Medicine, Department of Internal Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Centres, Vrije Universiteit, Amsterdam, the Netherlands.

Plastic and Reconstructive Surgery. Global Open

|February 9, 2024

Summary

Silicone migration occurred from intact saline breast implants in a 66-year-old patient experiencing breast implant illness. This case highlights potential risks of silicone leakage, even from non-silicone gel implants, necessitating further research.

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Area of Science:

Plastic Surgery
Biomaterials Science
Radiology

Background:

Breast augmentation commonly uses silicone gel-filled implants, with concerns focused on rupture and silicone leakage.
Silicone migration from intact saline breast implants is rare, but a potential concern.

Observation:

A 66-year-old patient presented with symptoms of breast implant illness.
Radiological imaging revealed silicone in axillary lymph nodes, despite intact saline breast implants.

Findings:

Histopathological evaluation confirmed silicone presence and a foreign body reaction in the axillary lymph nodes.
The polydimethylsiloxane shell of the saline implants is the likely source of silicone migration.

Implications:

This case highlights the potential for silicone migration from intact saline breast implants, challenging previous assumptions.
Further research is needed to understand the health implications of silicone particle leakage from all types of breast implants, particularly in the context of breast implant illness.