Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Local Anesthetics: Adverse Effects

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...

Blood and Nerve Supply to the Bones

Blood and Nerve Supply to the Bones

Bones are dynamic organs that require a rich supply of oxygen and nutrients. Around 5% to 10% of the cardiac output supplies blood to the bones. A typical long bone has three main sources: the nutrient artery, the metaphyseal and epiphyseal arteries, and the periosteal arteries.
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...

Disorders of the Nervous Tissue

Disorders of the Nervous Tissue

Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Orbital Lymphoma Presenting As Recurrent Orbital Cellulitis: A Diagnostic Challenge.

Cureus·2024

Same author

Eyelid Tumours in Northern Malaysia: A Five-Year Review.

Cureus·2022

Same author

Orbital Tumours in Northern Malaysia: A Five-Year Review.

Cureus·2022

See all related articles

Search research articles

Related Experiment Video

Updated: Jul 4, 2025

Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

Published on: April 19, 2024

A Nail in the Brain.

Tze Huei Kee¹, Khoo Chung Lee¹, Adlina Abdul Rahim¹

¹Ophthalmology, Hospital Sultanah Bahiyah, Alor Setar, MYS.

|February 9, 2024

Summary

A nail gun injury caused a severe eye and brain injury. While the patient recovered neurologically, the eye injury resulted in permanent vision loss, highlighting the need for workplace safety.

Area of Science:

Neurosurgery
Ophthalmology
Occupational Health

Background:

Transorbital penetrating brain injuries (TOPI) are uncommon, often resulting from high-velocity impacts.
Industrial accidents involving tools like nail guns pose significant risks for severe head and eye trauma.

Observation:

A 30-year-old male sustained a perforating left eye injury and intracranial foreign body from an accidental nail gun discharge at a construction site.
The nail penetrated the orbit, lodging in the frontal lobe, and caused orbital fractures and lacerations.

Findings:

Emergency bicoronal craniotomy successfully removed the intracranial nail.
The patient achieved a full neurological recovery (Glasgow Coma Scale 15) and was discharged on postoperative day 5.
Despite successful surgical intervention, the patient experienced complete vision loss (no perception of light) in the affected left eye.

Keywords:

industrial injury intracranial foreign body nail gun perforating eye injury transorbital

More Related Videos

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Published on: January 20, 2023

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

Related Experiment Videos

Last Updated: Jul 4, 2025

Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

Modified Mouse Model of Repetitive Mild Traumatic Brain Injury Incorporating Thinned-Skull Window and Fluid Percussion

Published on: April 19, 2024

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Published on: January 20, 2023

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

Published on: February 16, 2011

Implications:

This case underscores the severe consequences of work-related penetrating eye injuries.
Emphasizes the critical importance of stringent safety protocols and equipment maintenance in industrial settings to prevent such debilitating injuries.
Highlights the potential for significant visual morbidity even with successful neurosurgical management of intracranial foreign bodies.