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Conjunctival leiomyosarcoma: A clinico-pathological study with in deep molecular characterization.
Angela Santoro1, Giuseppe Angelico2, Antonino Mulè1
1General Pathology Unit, Department of Woman and Child's Health and Public Health Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, 00168 Rome, Italy.
Pathology, Research and Practice
|February 9, 2024
Summary
This study reports a rare conjunctival leiomyosarcoma (LMS) in an elderly male. Molecular analysis revealed a TSC1 gene mutation, suggesting potential mTOR inhibitor therapy for this orbital tumor.
Area of Science:
- Ophthalmology
- Oncology
- Genetics
Background:
- Orbital leiomyosarcomas (LMS) are known, but conjunctival LMS is extremely rare.
- This case involves a rapidly growing, painful mass in the nasal conjunctiva of a 97-year-old male.
