Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

L-dopa-induced asterixis.

I Kobayashi, M Osawa, K Ohta

    Folia Psychiatrica Et Neurologica Japonica
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Levodopa (L-dopa) can cause asterixis, a type of tremor, in some patients. This side effect, potentially linked to the dopaminergic system, resolved upon discontinuing the medication.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [The usefulness of high dose etoposide for peripheral blood stem cell harvest].

    Nihon Sanka Fujinka Gakkai zasshi·1996
    Same author

    Effect of high sucrose feeding on fat accumulation in the male Wistar rat.

    Obesity research·1996
    Same author

    Complications of childhood Sjögren syndrome.

    European journal of pediatrics·1996
    Same author

    Decreased serum 1,5-anhydroglucitol in nondiabetic subjects with a family history of NIDDM.

    Diabetes care·1996
    Same author

    Human cerebral activity with increasing inspiratory force: a study using positron emission tomography.

    Journal of applied physiology (Bethesda, Md. : 1985)·1996
    Same author

    Interferon-alpha potentiates the antiproliferative activity of CPT-11 against human colon cancer xenografts in nude mice.

    Anticancer research·1996
    Same journal

    Proceedings for the 9th meeting of the Japanese Society of Sleep Research. May 11-12, 1984, Kanazawa. Abstracts.

    Folia psychiatrica et neurologica japonica·1985
    Same journal

    Electron microscopic morphometric studies on synaptic vesicles of long-term CPZ-administered rat striatum.

    Folia psychiatrica et neurologica japonica·1985
    Same journal

    Movement-related cerebral potentials in schizophrenics.

    Folia psychiatrica et neurologica japonica·1985
    Same journal

    Expectancy-related cerebral potentials associated with voluntary time estimation and omitted stimulus.

    Folia psychiatrica et neurologica japonica·1985
    Same journal

    Clinicopathologic studies on neuro-Behçet's disease.

    Folia psychiatrica et neurologica japonica·1985
    Same journal

    Prognostic factors of primary generalized epilepsy: a reappraisal of 96 cases in terminal remission.

    Folia psychiatrica et neurologica japonica·1985
    See all related articles

    Area of Science:

    • Neurology
    • Pharmacology

    Background:

    • Levodopa (L-dopa) is a primary treatment for Parkinson's disease.
    • Understanding drug-induced side effects is crucial for patient management.

    Observation:

    • Three patients developed asterixis during L-dopa therapy.
    • Asterixis appeared without other L-dopa-related involuntary movements.
    • Associated symptoms included hallucinations, clouded consciousness, and insomnia.

    Findings:

    • Asterixis resolved after L-dopa withdrawal, suggesting a drug-related cause.
    • Normal liver and metabolic functions were noted in all cases.
    • The exact biochemical mechanism remains unclear, possibly involving dopaminergic or serotonergic pathways.

    Implications:

    Related Experiment Videos

    • Clinicians should consider L-dopa as a potential cause of asterixis.
    • Monitoring for asterixis and related symptoms is important during L-dopa treatment.
    • Further research into the neurochemical basis of this side effect is warranted.