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Functional alignment in robotic-assisted total knee arthroplasty: a systematic review
Filippo Migliorini1,2, Marco Pilone3, Luise Schäfer4
1Department of Orthopaedic, Trauma, and Reconstructive Surgery, RWTH University Medical Centre, Pauwelsstraße 30, 52074, Aachen, Germany. migliorini.md@gmail.com.
Archives of Orthopaedic and Trauma Surgery
|February 10, 2024
Summary
Functional alignment (FA) in robotic total knee arthroplasty (TKA) may enhance accuracy and implant positioning. Further high-quality trials are needed to confirm FA
Area of Science:
- Orthopedic Surgery
- Robotics in Medicine
- Biomechanical Engineering
Background:
- Robotic total knee arthroplasty (TKA) utilizes advanced technology for improved surgical precision.
- Functional alignment (FA) is an emerging technique in TKA aiming to optimize joint mechanics.
- Current evidence on FA in robotic TKA requires systematic evaluation.
Approach:
- A systematic review and meta-analysis was conducted following PRISMA guidelines.
- Searched PubMed, Web of Science, Google Scholar, and Embase for clinical studies on FA in robotic TKA.
- Evaluated risk of bias using Cochrane Handbook and ROBINS-I tools for non-RCTs.
Key Points:
- Reviewed seven studies involving 1198 patients with a mean follow-up of 17.1 months.
- Patients had a mean age of 67.2 years and a mean BMI of 30.9 kg/m².
- FA may offer benefits in terms of resection accuracy, implant alignment, and gap balancing.
Conclusions:
- Functional alignment shows potential to improve key aspects of robotic total knee arthroplasty.
- Additional high-quality clinical trials are necessary to establish FA's superiority over other alignment techniques.
- Long-term studies are required to assess the impact of FA on implant survivorship.

