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Published on: October 6, 2022
Multiple Cardiac Diseases Involving the Aortic Arch: Beating Heart Debranching, and Normothermic Arch Replacement: A
Alessandro Motta1, Cristian Scarpari1, Ermelinda Borrelli1,2
1UO Cardiochirurgia, APSS-Ospedale Santa Chiara, Largo Medaglie d'Oro, 38100 Trento, Italy.
Insights
This study introduces a "debranching first" surgical technique for complex aortic arch disease. The innovative approach minimizes ischemia, reducing risks and potentially offering a safer option for high-risk patients.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Aortic arch disease conventional management carries high morbidity and mortality.
- Optimizing neuroprotection, perfusion, and myocardial protection strategies remain challenging.
- Aortic arch replacement requires advanced surgical techniques to improve outcomes.
Purpose of the Study:
- To evaluate the safety and efficacy of a novel
- debranching first
- surgical technique for aortic arch disease.
- To assess the impact of this technique on patient outcomes, including ischemia time and complications.
- To determine the feasibility of this approach in patients with complex cardiac comorbidities.
Main Methods:
- A case series of 12 patients undergoing surgical management for aortic arch disease.
- Implementation of a
- debranching first
- technique involving supra-aortic vessel debranching on a beating heart.
- Subsequent cardiac and distal aortic arch repair steps to minimize ischemia.
Main Results:
- Six patients underwent aortic root replacement (Bentall or David procedure).
- Mean nasopharyngeal temperature was 34°C with a mean cardiocirculatory arrest time of 14.3 minutes.
- Early mortality was 8.3% (1 patient), with no permanent neurologic events.
Conclusions:
- The
- debranching first
- technique may reduce hypothermia, cardiopulmonary bypass, and myocardial arrest times.
- This approach could be a viable surgical option for complex aortic disease with concomitant cardiac conditions.
- The technique shows promise for improving outcomes, even in high-risk surgical candidates.
Abstract:
(1) Background: Conventional open surgery is still the gold standard for aortic arch disease, and despite recent developments in optimizing strategies for neuroprotection, distal organ perfusion, and myocardial protection, aortic arch replacement is still associated with high morbidity and mortality rates. (2) Methods: We present our case series of 12 patients undergoing surgical management of multiple cardiac diseases involving the aortic arch. In this single-center study, we report our initial experience over a five-year period (from December 2018 to October 2023) with the use of a "debranching first" technique for the supra-aortic vessels of a beating heart, followed by the cardiac step addressing proximal diseases, and a final distal step treating the aortic arch. This strategy aims to minimize cardiac, cerebral, and peripheral ischemia. (3) Results: Six patients underwent aortic root replacement with either Bentall (n = 4) or valve-sparing aortic root (David procedure) (n = 2). The mean nasopharyngeal temperature was 34 °C and the mean cardiocirculatory arrest was 14.3 min. The early mortality was 8.3% (1 patient); no patient experienced a permanent neurologic event. (4) Conclusions: In patients with complex aortic disease and concomitant cardiac disease, this approach reduces the need for hypothermia and decreases cardiopulmonary bypass time and myocardial arrest time and therefore could represent a valid surgical option, even in high-risk patients.
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