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Published on: February 23, 2020
New Directions in Diagnostics for Aortic Aneurysms: Biomarkers and Machine Learning
Kyle C Alexander1, John S Ikonomidis1, Adam W Akerman1
1Department of Surgery, Division of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Pioneering technologies, including machine learning (ML) and AI, are set to transform aortic aneurysm diagnosis and management. This review explores ML diagnostics, biomarkers, and their fusion for improved clinical tools.
Area of Science:
- Cardiovascular Medicine
- Medical Imaging
- Artificial Intelligence
Background:
- Aortic aneurysm disease, particularly thoracic aneurysms, presents significant diagnostic and management challenges.
- Existing diagnostic methods require enhancement for improved accuracy and efficiency.
Purpose of the Study:
- To review and appraise emerging technologies for aortic aneurysm diagnosis and management.
- To explore the role of machine learning (ML), computer-assisted diagnostics, and biomarkers in advancing aortic disease evaluation.
Main Methods:
- Comprehensive literature survey of contemporary and historical research on aortic aneurysm diagnosis.
- In-depth analysis of ML algorithms and computer-assisted diagnostic concepts.
- Synthesis of findings on circulating biomarkers from prior research and PubMed Central database.
Main Results:
- Machine learning and AI offer significant potential for revolutionizing aortic aneurysm diagnosis and management.
- Integration of AI-guided measurements and ML frameworks with biomarker analysis shows promise.
- Current research highlights challenges and future directions for translating AI into clinical practice.
Conclusions:
- The fusion of AI, ML, and biomarker analysis represents a transformative prospect for aortic aneurysm disease.
- Continued research and development are crucial for translating these technologies into practical diagnostic tools.
- This review provides a framework for understanding current advancements and future trajectories in aortic disease management.
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