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Updated: Jul 3, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
Long-Term Follow-Up of HRQoL up to Six Years after Outpatient Phase-II Cardiac Rehabilitation
Bianca Auschra1, Sebastian Euler1, Yara Zehnder1
1Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Insights
Health-related quality of life (HRQoL) improves with cardiac rehabilitation (CR) and remains stable long-term. Functional capacity at CR entry predicts better physical and mental HRQoL outcomes.
Area of Science:
- Cardiology
- Rehabilitation Medicine
- Health Psychology
Background:
- Low health-related quality of life (HRQoL) is linked to poor cardiovascular outcomes in coronary heart disease (CHD) patients.
- Cardiac rehabilitation (CR) is known to enhance HRQoL, but long-term changes and their predictors require further investigation.
Purpose of the Study:
- To assess long-term changes in HRQoL after CR.
- To identify predictors of sustained HRQoL improvements following CR in CHD patients.
Main Methods:
- A cohort of 153 CHD patients with complete SF-36 HRQoL data at CR entry, discharge, and follow-up was analyzed.
- Linear mixed-effects regression models were employed to examine predictors of long-term HRQoL, including clinical characteristics and functional capacity (6MWT).
Main Results:
- Significant improvements in both physical and mental HRQoL were observed from CR entry to discharge.
- These HRQoL enhancements were sustained at a mean four-year follow-up.
- Higher functional capacity (6MWT) at CR entry predicted better physical HRQoL and showed a trend towards predicting better mental HRQoL at follow-up.
- A pre-existing psychiatric diagnosis at CR entry was associated with better mental HRQoL at follow-up.
Conclusions:
- Improvements in HRQoL achieved during cardiac rehabilitation are maintained long-term.
- Functional capacity at the start of CR is a key predictor for sustained physical and mental HRQoL.
- These findings highlight the importance of functional status in managing long-term HRQoL for CHD patients.
Abstract:
Background: Low health-related quality of life (HRQoL) is associated with adverse cardiovascular outcomes in coronary heart disease (CHD) patients. Cardiac rehabilitation (CR) improves HRQoL; however, evidence on long-term HRQoL changes after CR, and their predictors, is missing. Methods: A total of 153 patients with complete HRQoL data in the short-form (SF)-36 Health Survey at CR entry, discharge and follow-up were included. Using linear mixed-effects regression models for repeated time measurements, we examined predictors of follow-up HRQoL, including age and clinical characteristics. Results: Both physical (t = -5.66, p < 0.001) and mental (t = -2.06, p = 0.040) HRQoL improved significantly from CR entry to discharge, with improvements remaining stable over a mean follow-up of four years (range 2.4-6.1). Better functional capacity (6MWT) at CR entry predicted better physical HRQoL (t = 5.50, p < 0.001) and, with a trend, better mental HRQoL (t = 1.92, p = 0.056) at follow-up. A psychiatric diagnosis at CR entry predicted better mental HRQoL at follow-up (t = 3.85, p < 0.001). Conclusions: Improvements in HRQoL during CR remain stable during long-term follow-up. Levels of functional capacity appear to be relevant to both physical and mental HRQoL at follow-up.
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