Preparation, Characterization, and Antioxidant Activities of Extracts from Amygdalus persica L. Flowers

Qingtao Yu ^1,2, Wenzhi Li ², Ming Liang ²

⁰Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China.

Molecules (basel, Switzerland) +

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February 10, 2024

View abstract on PubMed

Summary

A novel peach flower polysaccharide (APL) exhibits potent antioxidant and depigmenting properties. This natural compound effectively reduces oxidative stress and tyrosinase activity, showing promise for cosmetic and food applications.

Area Of Science

Phytochemistry
Pharmacology
Cosmetic Science

Background

Polysaccharides from natural sources are increasingly investigated for their biological activities.
Amygdalus persica L. flowers represent an underutilized resource with potential bioactive compounds.
Understanding the chemical structure and functional properties of plant-derived polysaccharides is crucial for their application.

Purpose Of The Study

To isolate and characterize a novel water-soluble polysaccharide from Amygdalus persica L. flowers.
To evaluate the antioxidant activities of the isolated polysaccharide in vitro and in vivo.
To investigate the potential depigmenting effects of the polysaccharide by assessing tyrosinase activity and melanin content.

Main Methods

Hot water extraction and purification of the polysaccharide (APL).
Structural analysis using Infrared spectroscopy (IR), Gas Chromatography-Mass Spectrometry (GC-MS), and High-Performance Liquid Chromatography (HPLC).
In vitro antioxidant assays (DPPH, ABTS, hydroxyl radical, superoxide radical scavenging, reducing power) and in vivo studies using zebrafish embryos exposed to LPS.

Main Results

A novel water-soluble polysaccharide (APL) was successfully isolated, composed of rhamnose, arabinose, mannose, and glucose, with an average molecular weight of approximately 208.53 kDa and 15.19 kDa.
APL demonstrated significant antioxidant activity in vitro and effectively reduced LPS-induced oxidative stress in zebrafish embryos.
APL treatment led to a reduction in tyrosinase activity and total melanin content in zebrafish embryos, indicating potential depigmenting effects.

Conclusions

The isolated polysaccharide from Amygdalus persica L. flowers possesses significant antioxidant properties.
APL shows potential as a natural agent for reducing oxidative stress and hyperpigmentation.
This study highlights the value of Amygdalus persica L. flowers as a source for developing natural antioxidants and cosmetic ingredients.

Keywords:

Amygdalus persica L. flowers antioxidant activity polysaccharide structural characterization