Role of Adipose Tissue Hormones in Pathogenesis of Cryptoglandular Anal Fistula

Marcin Włodarczyk1, Jakub Włodarczyk1,2, Kasper Maryńczak1

  • 1Department of General and Oncological Surgery, Faculty of Medicine, Medical University of Lodz, Pomorska 251, 92-213 Lodz, Poland.

Summary

Hormones from adipose tissue, including leptin and resistin, are linked to complex perianal fistulas. Reduced adiponectin and altered epithelial-to-mesenchymal transition (EMT) factors are observed in these challenging cases.

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