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Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
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Special Issue "Deployment of Proteomics Approaches in Biomedical Research"

Joaquín Fernández-Irigoyen1, Enrique Santamaría1

  • 1Proteomics Platform, Clinical Neuroproteomics Unit, Navarrabiomed, Hospitalario Universitario de Navarra (HUN), Navarra Institute for Health Research (IDISNA), Universidad Pública de Navarra (UPNA), Irunlarrea 3, 31008 Pamplona, Spain.

International Journal of Molecular Sciences
|February 10, 2024
PubMed

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Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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