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Phenibut: Review and Pharmacologic Approaches to Treating Withdrawal

Scott R Penzak1, Marilyn Bulloch1

  • 1Department of Pharmacy Practice, Harrison College of Pharmacy, Auburn University, Auburn, AL, USA.

Journal of Clinical Pharmacology
|February 10, 2024
PubMed
Summary

Phenibut, a GABA analog, is increasingly causing intoxication and withdrawal. Baclofen, benzodiazepines, and phenobarbital effectively treat withdrawal symptoms, with phenobarbital recommended for seizure risk.

Keywords:
GABAaddiction medicinebaclofenbenzodiazepinesclinical pharmacology (CPH)drug abusephenibutphenobarbitaltoxicology (TOX)withdrawal

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