[Hypercalcemia-hypocalciuria syndrome. Apropos of 2 cases]

Two patients with urinary calculi presented hypercalcemia with very moderate calciuria and serum parathormone levels. These cases are used as a basis for a description of the familial hypercalcemia-hypocalciuria syndrome reported by Marx, a dominant autosomal disease in which the hypercalcemia is associated with a moderate hypermagnesemia and normal renal function. Pathogenesis is related to an increase in tubular reabsorption of Ca++ and Mg++. Surgery to parathyroids would be of no value since these glands are normal.