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How Does Anticipated HIV Stigma Affect Medication Adherence? A Longitudinal Path Analysis Model.

Guangzhe Frank Yuan1,2, Shan Qiao3,4, Xiaoming Li3,4

  • 1School of Education Science, Leshan Normal University, Leshan, Sichuan, China. yb97316@umac.mo.

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Summary

Anticipated HIV stigma impacts medication adherence in people living with HIV (PLWH). Support and self-management longitudinally mediate this link, offering intervention insights.

Keywords:
Anticipated HIV stigmaHIV self-managementMedication adherenceMedication adherence supportPLWH

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Area of Science:

  • Public Health
  • Psychology
  • Longitudinal Studies

Background:

  • Anticipated HIV stigma is linked to medication adherence in people living with HIV (PLWH).
  • Longitudinal data on the mechanisms connecting stigma and adherence are limited.
  • Understanding these mechanisms is crucial for effective interventions.

Purpose of the Study:

  • To investigate the longitudinal mediation effects of medication adherence support and HIV self-management.
  • To explore the pathway from anticipated HIV stigma to medication adherence over time.
  • To identify key factors influencing medication adherence among Chinese PLWH.

Main Methods:

  • A four-wave longitudinal study with 1,098 Chinese PLWH.
  • Data collected via self-report questionnaires at six-month intervals.
  • Path analysis used to examine mediation models.

Main Results:

  • Anticipated HIV stigma at baseline predicted medication adherence at Time 4.
  • Medication adherence support (Time 2) and HIV self-management (Time 3) serially mediated this relationship.
  • This highlights a sequential pathway from stigma to adherence.

Conclusions:

  • Medication adherence support and HIV self-management are critical mediators.
  • Findings inform the development of targeted interventions for PLWH facing stigma.
  • Public health strategies can be refined to improve adherence in this population.