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Updated: Jul 3, 2025

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Pediatric patients diagnosed as overweight and obese have an elevated risk of dyspnea
Lydia S Robson1, Abidan Abulimiti2, Jorge Z Granados2
1Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, USA.
Insights
Pediatric patients with overweight and obesity face a higher risk of dyspnea (shortness of breath). This finding highlights the importance of weight management in children
Area of Science:
- Pediatric Pulmonology
- Obesity Medicine
- Clinical Epidemiology
Background:
- Overweight and obesity are increasing globally in pediatric populations.
- Dyspnea (shortness of breath) is a common respiratory symptom in children.
- The association between pediatric overweight/obesity and dyspnea requires further investigation.
Purpose of the Study:
- To determine if pediatric patients (aged 8-12 years) with overweight and obesity have a higher likelihood of experiencing dyspnea compared to non-overweight peers.
- To analyze the risk of dyspnea associated with overweight and obesity in a large, multi-center pediatric cohort.
Main Methods:
- Utilized de-identified data from the global federated TriNetX research network, including UT Southwestern Medical Center.
- Included pediatric patients aged 8-12 years.
- Identified overweight/obesity using ICD-10-CM codes (E66) and dyspnea using code R06.0.
Main Results:
- Patients with overweight and obesity demonstrated a significantly higher risk of dyspnea in both the UT Southwestern Network (RR: 1.81, p < 0.001) and the Research Network (RR: 2.70, p < 0.001).
- Within the UT Southwestern Network, females exhibited a higher risk of dyspnea compared to males (RR: 2.17 vs. 1.67).
- The association remained significant across different network settings.
Conclusions:
- Overweight and obesity are independently associated with an increased risk of dyspnea in pediatric patients aged 8-12 years.
- Clinicians should consider weight status as a potential risk factor for dyspnea in children, prompting further evaluation.
- This highlights the need for early intervention and management of pediatric obesity to mitigate respiratory complications.
Abstract:
We investigated whether pediatric patients with overweight and obesity are more likely to have dyspnea compared with those who are non-overweight. We collected de-identified data from TriNetX, a global federated multicenter research database, using both the UT Southwestern Medical Center and multinational Research Networks. Our analysis focused on patients aged 8-12 years. We identified overweight and obesity using ICD-10-CM codes E66 and dyspnea using code R06.0. Patients with overweight and obesity had a significantly higher risk of dyspnea compared with those who were non-overweight. This association was observed in both the UT Southwestern Network (risk ratio: 1.81, p < 0.001) and the Research Network (risk ratio: 2.70, p < 0.001). Furthermore, within the UT Southwestern Network, the risk was found to be higher in females compared with males (risk ratio: 2.17 vs. 1.67). These results have significant clinical implications, suggesting that clinicians should consider overweight and obesity as independent risk factors for dyspnea in pediatric patients after excluding other possible contributing factors.
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