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Prodromal multiple sclerosis: considerations and future utility
Katharine E Harding1, Karim L Kreft2, Yoav Ben-Shlomo3
1Department of Neurology, Aneurin Bevan University Health Board, Royal Gwent Hospital, Cardiff Road, Newport, NP20 2UB, UK. katharineharding@doctors.org.uk.
Journal of Neurology
|February 11, 2024
Summary
A multiple sclerosis (MS) prodrome, characterized by increased healthcare use and specific symptoms before diagnosis, offers potential for early intervention and disease management. Further research is needed to answer key questions about its length and symptom specificity.
Area of Science:
- Neurology
- Clinical Research
Background:
- A multiple sclerosis (MS) prodrome, marked by heightened healthcare utilization and symptoms like fatigue and pain, precedes clinical diagnosis.
- Understanding the MS prodrome is crucial for identifying risk factors, potentially delaying onset, and altering disease course.
Conclusions:
- The MS prodrome has significant potential for early detection, risk stratification, and influencing clinical trials.
- Further research is essential to fully understand and leverage the MS prodrome for improved MS management and public health strategies.
