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Advances in functional coatings on biliary stents
Kaining Yang1, Wenxin Sun1, Lanyue Cui2
1Department of Bioengineering, College of Chemical and Biological Engineering, Shandong University of Science and Technology, Qingdao 266590, China.
Regenerative Biomaterials
|February 12, 2024
Summary
Functional coatings on biliary stents show promise for preventing complications like infection and restenosis. Further research is needed to balance medication effectiveness and safety for improved patient outcomes.
Area of Science:
- Biomedical Engineering
- Materials Science
- Gastroenterology
Background:
- Biliary stenting is crucial for treating biliary tract diseases but faces challenges like infection and restenosis.
- The biliary system's complexity and bile composition contribute to stent-related complications.
Purpose of the Study:
- To review advancements in functional coatings for biliary stents.
- To explore applications including anticorrosion, antibacterial, antitumor, stone-dissolving, X-ray visibility, and anti-migration properties.
- To discuss future trends and challenges in this field.
Main Methods:
- Review of cutting-edge research on functional coatings for biliary stents.
- Analysis of seven key coating perspectives: anticorrosion, antibacterial, antitumor, stone-dissolving, X-ray visibility, anti-migration, and composite coatings.
- Discussion of current development trends and experimental validation.
Main Results:
- Functional coatings demonstrate significant potential in addressing biliary stent complications.
- Coatings show promise in anticorrosion, antibacterial, antitumor, stone dissolution, and enhancing X-ray visibility.
- Many coatings have advanced to animal experiment levels, providing a basis for human studies.
Conclusions:
- Combining functional coatings with biliary stents offers innovative solutions for biliary tract diseases.
- Optimizing the balance between medication efficacy and safety is crucial for clinical translation.
- Further development holds great potential for improving patient care and outcomes in biliary interventions.
