Related Experiment Video
Updated: Jul 3, 2025
10:41
A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
Published on: April 30, 2020
14.0K
Disseminated tuberculosis presented with explicit hypercalcemia: A clinical case report
Seyed Ali Dehghan Manshadi1, Nahid Shafiee2, Seyed Mohammad Piri3
1Department of Infectious Disease and Tropical Medicine/ Iranian Research Center for HIV/AIDS (IRCHA) Tehran University of Medical Sciences Tehran Iran.
Clinical Case Reports
|February 12, 2024
Summary
Tuberculosis (TB) can cause hypercalcemia, especially in patients with existing health issues. Treating TB with anti-TB drugs alongside standard hypercalcemia management is crucial for recovery.
Area of Science:
- Endocrinology
- Infectious Diseases
- Nephrology
Background:
- Hypercalcemia, a calcium level exceeding 10.5 mg/dL, is an uncommon manifestation of tuberculosis (TB).
- Patients with comorbidities like renal failure, diabetes, or severe anemia are at higher risk.
- Refractory or resistant hypercalcemia necessitates consideration of TB as a potential underlying cause.
Observation:
- A small percentage of patients with TB develop symptomatic hypercalcemia.
- Disseminated TB can present with persistent hypercalcemia, particularly in young adults.
- Underlying conditions significantly influence the prognosis of TB-related hypercalcemia.
Findings:
- The study highlights a case of a young adult with disseminated TB and persistent hypercalcemia.
- Effective management involved a combination of standard hypercalcemia treatments and anti-tuberculosis drugs.
- Anti-TB therapy was essential in normalizing calcium levels in this patient.
Implications:
- Clinicians should consider tuberculosis in the differential diagnosis of unexplained hypercalcemia.
- Integrated treatment strategies combining anti-TB medications and hypercalcemia management are vital.
- Early diagnosis and treatment of TB-related hypercalcemia can improve patient outcomes.
Related Concept Videos
01:31Pulmonary Tuberculosis III
327
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
327
01:28Pulmonary Tuberculosis II
237
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
237
01:26Pulmonary Tuberculosis IV
143
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
143
01:29Pulmonary Tuberculosis I
243
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
243
01:28Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180