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Published on: April 25, 2014
Giant Coronary Artery Aneurysms Presenting As Posterior Myocardial Infarction
Syed M Ishaq1, Sanchit Duhan1, Bijeta Keisham2
1Internal Medicine, Sinai Hospital of Baltimore, Baltimore, USA.
Insights
Coronary artery aneurysms (CAAs) are vessel dilatations that can mimic acute coronary syndromes. Medical management, including beta-blockers, statins, and anticoagulation, proved effective for a patient with multiple CAAs and pulmonary hypertension.
Area of Science:
- Cardiology
- Vascular Medicine
Background:
- Coronary artery aneurysm (CAA) is defined as a vessel dilatation ≥1.5 times the adjacent normal diameter.
- Giant CAAs lack a universally accepted definition, highlighting a gap in current classifications.
Observation:
- A 45-year-old male presented with substernal chest pain, ECG changes (ST depression, T wave inversions), but normal cardiac biomarkers.
- Cardiac catheterization revealed CAAs in the right coronary artery (RCA), left anterior descending (LAD), and left circumflex (LCX) arteries.
- The patient had severe pulmonary hypertension, posing a high risk for surgical intervention.
Findings:
- Medical management with beta-blockers, high-intensity statin, and warfarin anticoagulation was initiated.
- The patient remained asymptomatic at a two-month follow-up, indicating successful conservative treatment.
Implications:
- Coronary artery aneurysms can manifest as acute coronary syndromes, necessitating prompt diagnosis.
- Treatment strategies for CAAs are evolving, encompassing medical, percutaneous, and surgical options.
- This case underscores the viability of medical management for selected CAA patients, particularly those with high surgical risk.
Abstract:
A coronary artery aneurysm (CAA) is defined as the dilatation of a vessel with a diameter of ≥1.5 times that of the adjacent normal vessel. Occasionally, aneurysms can be large enough to be characterized as giant CAAs, but there is no universally accepted definition. We discuss the case of a 45-year-old male patient who presented to the hospital with substernal chest pain. His ECG revealed ST depression and T wave inversions in precordial leads. Cardiac biomarkers were within normal limits. Due to concerns about coronary artery disease, cardiac catheterization was done, which revealed CAAs in the distribution of the right coronary artery (RCA), left anterior descending (LAD) and left circumflex (LCX) artery. The patient was at high risk for surgical intervention given coexisting severe pulmonary hypertension. Therefore, medical treatment was initiated with beta-blockers, high-intensity statin, and anticoagulation with warfarin. In a two-month follow-up, the patient remained asymptomatic without any residual symptoms. A CAA can present as an acute coronary syndrome. The treatment still evolves, involving medical management and/or percutaneous or surgical interventions.
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