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Related Experiment Video

Updated: Jul 3, 2025

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Sinonasal Symptom Correlation With the Postoperative Polyp Scale (POPS).

Arthur W Wu1,2, Erika A Garcia Ruiz2, Thomas S Higgins1,3

  • 1Snot Force Alliance, Inc., Louisville, KY, USA.

The Annals of Otology, Rhinology, and Laryngology
|February 12, 2024
PubMed
Summary

The Postoperative Polyp Scale (POPS) shows moderate correlation with overall sinonasal symptoms and strong correlation with rhinologic symptoms, making it a promising tool for evaluating patients with chronic rhinosinusitis with nasal polyps (CRSwNP). This new grading system offers improved assessment compared to older methods.

Keywords:
SNOT-22chronic rhinosinusitisendoscopic sinus surgeryendoscopygradingnasal polypspostoperativerhinologicscalessinonasalsinusitis

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Area of Science:

  • Otolaryngology
  • Rhinology
  • Surgical Outcomes Assessment

Background:

  • Traditional endoscopic nasal polyp grading scales demonstrate poor correlation with patient-reported outcomes and symptom severity.
  • The Postoperative Polyp Scale (POPS) was developed to provide a more accurate characterization of polyp recurrence in the context of surgically altered sinus cavities.

Purpose of the Study:

  • To investigate the correlation between the Postoperative Polyp Scale (POPS) and sinonasal symptom scores in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).

Main Methods:

  • Prospective study involving CRSwNP patients administered the SNOT-22 questionnaire.
  • Patients were graded using the POPS starting at their 1-month postoperative appointments.
  • Total and Max POPS scores were correlated with SNOT-22 total scores and subdomains using Kendall correlation testing.

Main Results:

  • A significant correlation was observed between both Total POPS and Max POPS scores and the SNOT-22 total score (P < .001).
  • POPS scores demonstrated significant correlations across all SNOT-22 subdomains: Rhinologic, Extra-Nasal Rhinologic, Ear/Facial, and Psychologic.
  • Strong correlation was found with the Rhinologic subdomain, moderate with Extra-Nasal Rhinologic and Ear/Facial, and weak with the Psychologic subdomain.

Conclusions:

  • The POPS demonstrates a moderate correlation with overall sinonasal symptoms (SNOT-22 total score) and a strong correlation with the key Rhinologic subdomain.
  • These findings suggest the POPS holds significant potential as an effective tool for assessing postoperative outcomes in CRSwNP patients.
  • The POPS offers a more clinically relevant grading system compared to previous scales, better reflecting patient symptomology.