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A Clinicopathological Appraisal of Duodenal Neuroendocrine Tumors at a Racially Diverse Safety Net Hospital
Sofia D Shaikh1,2, Isa Jacoba3, Natalie Sun1
1Section of General Internal Medicine, Boston Medical Center, Boston, Massachusetts, USA.
Introduction:
Significant knowledge gaps exist regarding clinicopathological profiling as well as treatment, surveillance, and survival of duodenal neuroendocrine tumors (dNETs).
Methods:
We clinicopathologically characterized and identified racial differences among patients with dNETs at a large safety net hospital. Tumor grades were updated based on the World Health Organization 2019 NET classification, and overall survival was determined.
Results:
We identified 17 dNETs and found no differences in clinicopathologic characteristics across racial groups. Pathological diagnosis was upgraded in 35% of dNETs, and age >65 years significantly shortened overall survival.
Discussion:
Larger-scale studies are needed to determine the significance of these findings.
