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Updated: Jul 3, 2025

Separation of Mouse Embryonic Facial Ectoderm and Mesenchyme
Published on: April 12, 2013
Genetics and Epigenetics in the Genesis and Development of Microtia
Xin Chen1, Jing Ma1, Tianyu Zhang1,2
1Department of Facial Plastic and Reconstructive Surgery, ENT Institute, Eye & ENT Hospital, Fudan University.
Abstract:
Microtia is a congenital malformation of the external and middle ear associated with varying degrees of severity that range from mild structural abnormalities to the absence of the external ear and auditory canal. Globally, it is the second most common congenital craniofacial malformation and is typically caused by inherited defects, external factors, or the interaction between genes and external factors. Epigenetics notably represents a bridge between genetics and the environment. This review has devoted attention to the current proceedings of the genetics and epigenetics of microtia and related syndromes.
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