Blue-Light Filtering Monofocal Intraocular Lenses: A Study on Optical Function and Tolerance to Misalignment

Area of Science:

• Ophthalmology
• Optical Engineering
• Biomedical Optics

Background:

• Blue-light filtering monofocal intraocular lenses (IOLs) are crucial for cataract surgery.
• Assessing optical performance and tolerance to misalignment is vital for IOL selection.
• Understanding the impact of aberrations and misalignment on visual quality is essential.

Purpose of the Study:

• To investigate and compare the optical performance of two blue-light filtering monofocal IOLs.
• To evaluate the tolerance to misalignment (decentration and tilt) of these IOLs.
• To determine the impact of spherical aberration (SA) and chromatic aberration on IOL performance.

Main Methods:

• Optical properties of CT Lucia 621 PY and Clareon CNA0T0 IOLs were assessed using modulation transfer function (MTF).
• Testing was conducted in monochromatic and polychromatic light with varying pupil sizes (3-mm and 4.5-mm) and induced spherical aberration.
• IOLs were subjected to simulated misalignment, including decentration (up to 1 mm) and tilt (5 degrees).

Main Results:

• CT Lucia 621 PY showed slightly higher MTF at 50 lp/mm under monochromatic conditions (0.77 vs 0.69).
• CT Lucia 621 PY maintained minimally better performance with SA and chromatic aberration.
• The CT Lucia 621 PY exhibited better tolerance to tilt and decentration across all tested conditions.

Conclusions:

• Both IOLs demonstrated similar optical quality and simulated visual acuity.
• The CT Lucia 621 PY's aspheric design provides an advantage in imperfect physiological conditions.
• CT Lucia 621 PY offers more robust performance under tilt and decentration, indicating superior clinical adaptability.